13th seed Ana Ivanovic (Player Profile) took on the challenge of qualifier Christina McHale (Player Profile) on Arthur Ashe after three seeds – Kvitova, Kirilenko and Kuznetsova – had all been beaten early on Saturday. In a day of remarkable surprise results, Ivanovic looked to be on the verge of defeat against the 114th ranked American who had not gone beyond the second round in any of her tournaments this year. McHale took the first tight set 6-4 and led 5-4 on her serve in the second set, but the Serb managed to break back and took the set 7-5. In the decider Ivanovic got the crucial break late in the set to take it 6-4 and win a match that took almost two and a half hours to complete.
On Louis Armstrong Stadium 2nd seed Vika Azarenka (Player Profile) faced former top 10 and 26th seeded Frenchwoman, Alize Cornet (Player Profile). Cornet beat two qualifiers in straight sets in her first two matches, while Azarenka lost just four games in her first two rounds. The story on Saturday was very different for the Belarusian, as Cornet went up 4-1 in the first set before her opponent managed to level and take the set to a breaker. Again Cornet got the upper hand and took it 7-2. Games went with serve for the first four games of the second set before Azarenka took the set 6-3. Even though the 2nd seed took the decider 6-2, she was still made to work hard for every point, as the almost three hours on court confirmed.
48th ranked Slovak veteran Daniela Hantuchova (Player Profile) also dropped the first set in her match against the 128th ranked Israeli qualifier Julia Glushko (Player Profile). Age and experience won out in the end after Glushko took the first set 6-3 and led 4-1 and 5-2 30-0 in the second set, but Hantuchova fought back to level, break and serve out the set at 7-5. She then led 3-0 in the decider before the Israeli clawed back to level and go ahead 5-4 with four match points which heartbreakingly she was unable to convert. The set went to a breaker where the Slovak led 6-2, but dropped two match points before taking it 7-4 after two hours and forty six minutes on court.
In one of the night matches, 6th seed Caroline Wozniacki (Player Profile) was another high seeded casualty when she lost a tight match against the Italian qualifier, Camila Giorgi (Player Profile), who is ranked at 136. Wozniacki took the first set 6-4 but the Italian, looking in peak condition and starting to play a very aggressive game, took the second set by the same margin. In the decider Giorgi led 5-2 with three match points, but Wozniacki saved them all and took the game before Giorgi served out the set at 6-3 with another magnificent forehand winner after playing for just over two and a half hours.